Honokiol suppresses metastasis of renal cell carcinoma by targeting KISS1/KISS1R signaling

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Honokiol suppresses metastasis of renal cell carcinoma by targeting KISS1/KISS1R signaling

Renal cell carcinoma (RCC) is a common urological cancer worldwide and is known to have a high risk of metastasis, which is considered responsible for more than 90% of cancer associated deaths. Honokiol is a small-molecule biphenol isolated from Magnolia spp. bark and has been shown to be a potential anticancer agent involved in multiple facets of signal transduction. In this study, we demonstr...

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gingival metastasis of renal cell carcinoma

metastases of internal tumors to the oral cavity are unusual and in most cases involve maxilla and mandible. metastases to the gingival soft tissue are extremely rare. reporting a new clinical case of renal cell carcinoma (rcc) metastasis with an unusual site. metastatic involvement of gingival tissue with renal cell carcinoma is an extremely rare clinical event. it is usually associated with i...

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ژورنال

عنوان ژورنال: International Journal of Oncology

سال: 2015

ISSN: 1019-6439,1791-2423

DOI: 10.3892/ijo.2015.2950